Obaberine

Reference work entry

CAS Registry Number: 1263-80-5 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Bisisoquinoline Alkaloids

Biological sources: Berberis iliensis, B. nummularia

C38H42N2O6: 622.3043

Mp: 139–140°C, 180°C (picrate) [1]

[α]D +144° (EtOH) [1]

MSm/z: 622(M+), 621, 515, 431, 430, 396, 395, 381, 361, 349, 335, 311(++), 198(++), 175(++), 174 [2]

1H NMR: 2.58(3H, s, 2-NCH3), 2.67(3H, s, 2′-NCH3), 3.19(3H, s, 7′-OCH3), 3.63(3H, s, 6-OCH3), 3.64(H-1), 3.78(3H, s, 6′-OCH3), 3.89(3H, s, 12-OCH3),4.21(H-1′), 5.45(H-10), 6.32(H-5′), 6.36(H-5), 6.37(H-11′), 6.64(H-8), 6.76(H-13), 6.79(H-14), 6.94(H-10′, H-13′) [3]

Pharm./Biol.: Anti-inflammatory action [4]

References

  1. 1.
    A. Karimov, R. Shakirov, Chem. Nat. Comp. 29, 69 (1993)Google Scholar
  2. 2.
    J. Baldas, I.R.C. Bick, T. Ibuka, R.S. Kapil, Q.N. Porter, J. Chem. Soc. Perkin. Trans. 1, 592 (1972)Google Scholar
  3. 3.
    H. Guinaudeau, A.J. Freyer, M. Shamma, Nat. Prod. Rep. 3, 477 (1986)Google Scholar
  4. 4.
    F.S. Sadritdinov, Med. Zh. Uzb. (2), 54 (1980)Google Scholar

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© Springer Science+Business Media New York 2013

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