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Cycleanine

Reference work entry

CAS Registry Number: 518-94-5 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Stephania delavayi, S.glabra

C38H42N2O6: 622.3043

Mp: 272–273°C (EtOH), 311°C (methiodide), 193°C (picrate) [1]

[α]D −12° (CHCl3) [1]

UV: 232 sh, 276, 285 sh(4.87, 3.89, 3.83) [2]

IR: 1608, 1505, 1490, 1452, 1415, 1375, 1340, 1293, 1220, 1170, 1145, 1115, 1068, 1017, 843, 805 [2]

MSm/z: 622(M+, 29), 621(8), 313(26), 312(100), 311(28), 204(21), 190(17), 174(17), 159(14), 146(7), 145(8) [2]

1H NMR: 2.53(6H, s, 2 × NCH3), 3.38(6H, s, 2 × OCH3), 3.78(6H, s, 2 × OCH3), 6.13–7.05(10H, m, H–Ar) [2]

Pharm./Biol.: Anti-inflammatory, analgetic, antipyretic action [3]

References

  1. 1.
    I.I. Shchelchkova, T.N. Il’inskaya, A.D. Kuzovkov, Chem. Nat. Comp. 1, 210 (1965)Google Scholar
  2. 2.
    D. Dwuma-Badu, J.C.K. Ayim, C.A. Mingle, A.N. Tackie, D.J. Slatkin, J.E. Knapp, P.L. Schiff, Phytochemistry 14, 2520 (1975)Google Scholar
  3. 3.
    I.M. Rabinovich, P.N. Kibal’chich, I.I. Fadeeva, T.N. Il’inskaya, A.D. Kuzovkov, V.V. Berezhinskaya, E.A. Trutneva, S.S. Nikitina, Aptechn. delo 6, 19 (1965)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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