Intebrimine

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Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Benzylisoquinoline Alkaloids

Biological sources: Berberis integerrima

C20H25NO4: 343.1783

Mp: oil, 171–172°C (hydrochloride) [1]

Solubility: very sol. org. solvs [1]

UV: 208, 230 sh, 285(4.31, 3.84, 3.69) [1]

IR: 2900, 2540, 1600, 1480, 1440, 1110 [1]

MSm/z: 343(M+, 25), 342(23), 328(2), 206(3), 192(100), 176(6), 164(63), 151(82) [1]

1H NMR: 2.82(4H, m, H-3, H-4), 3.56(2H, s, H-α), 3.62(2H, s, H-1), 3.81(6H, s, 2 × OCH3), 3.84(6H, s, 2 × OCH3), 6.49(1H, s, H-5), 6.60(1H, s, H-8), 6.78(1H, d, J = 8.5, H-5′), 6.90(1H, dd, J = 8.5; 1.8, H-6′), 6.98(1H, d, J = 1.8, H-2′) [1]

References

  1. 1.
    A. Karimov, V.I. Vinogradova, R. Shakirov, Chem. Nat. Comp. 29, 57 (1993)Google Scholar

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© Springer Science+Business Media New York 2013

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