Bernumine

Reference work entry

CAS Registry Number: 169134-46-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Benzylisoquinoline Alkaloids

Biological sources: Berberis nummularia

C19H21NO4: 327.1465 [1]

Mp: oil [1]

[α]D +33°C (CHCl3) [1]

UV: 285(3.84) [1]

IR: 3450 [1]

MSm/z: 327(M+, 2), 312(55), 192(2, 5), 190(2), 178(5, 5), 135(100) [1]

1H NMR: 1.30(3H, d, J = 6.6, CH3), 2.30–3.20(4H, m), 3.58, 3.64(each 1H, d, J = 13.5, H-9), 3.74(1H, q, J = 6.6, H-1), 3.75(3H, s, OCH3), 5.92(2H, s, CH2O2), 6.42(1H, s, H-8), 6.56(1H, s, H-5), 6.65(1H, d, J = 8, H-14), 6.74(1H, d, J = 8, H-15), 6.87(1H, d, J = 1.5, H-11) [1]

13 C NMR: [ 1]

Table 1

C-1

55.5

C-8

109.4

C-13

146.5

3

43.2

8a

132.2

14

109.3

4

25.7

9

57.3

15

121.9

4a

126.1

 10

130.5

CH3

20.0

5

114.3

 11

107.8

OCH3

55.8

6

143.9

 12

147.5

CH2O2

100.8

7

145.0

       

References

  1. 1.
    A. Karimov, M.G. Levkovich, N.D. Abdullaev, R. Shakirov, Chem. Nat. Comp. 29, 335 (1993)Google Scholar

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