Advertisement

Thalicsimidine

Reference work entry

Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Thalictrum filamentosum, T. longipedunculatum, T. minus, T. simplex, T. strictum

C22H27NO5: 385.1889

Mp: 131–132°C (EtOH), 252°C (dec., hydrobromide), 202°C (dec., sulfate), 150°C (picrate), 225°C (methiodide) [1]

[α]D +20° (CHCl3) [1], +57° (EtOH) [1]

UV: 220, 280, 300 [1]; 273, 282, 303, 312(4.26, 4.36, 4.33, 4.29) [2]

MSm/z: 385(M+, 100), 384(74), 370(50), 354(21), 342(33), 327(17), 311(33), 280(26), 57, 56, 55, 43 [3, 4]

1H NMR: 2.47(3H, s, NCH3), 3.64(3H, s, 1-OCH3), 3.82(3H, s, 2-OCH3), 3.85(6H, s, 9-OCH3, 10-OCH3), 3.88(3H, s, 3-OCH3), 6.70(1H, s, H-8), 7.89(1H, s, H-11) [3]

References

  1. 1.
    Kh.S. Umarov, M.V. Telezhenetskaya, Z.F. Ismailov, S.Yu. Yunusov, Chem. Nat. Comp. 3, 299 (1967)Google Scholar
  2. 2.
    P.E. Sonnet, M.J. Jacobson, J. Pharm. Sci. 60, 1254 (1971)Google Scholar
  3. 3.
    Z.F. Ismailov, M.V. Telezhenetskaya, S.Yu. Yunusov, Chem. Nat. Comp. 4, 117 (1968)Google Scholar
  4. 4.
    Z.F. Ismailov, S.Yu. Yunusov, Chem. Nat. Comp. 4, 169 (1968)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations