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Thalicminine

Reference work entry

CAS Registry Number: 16408-77-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Thalictrum flavum, T. isopyrodes, T. longipedunculatum, T. minus, T. simplex, T. strictum

C20H15NO6: 365.0899

Mp: 263–265°C (CHCl3) [1], 275–277°C [2]

UV: 252, 282, 364, 456(4.29, 4.43, 3.91, 3.72) [1]

IR: 2850, 1650, 1280, 1150 [1]

MSm/z: 365, 350, 335, 322, 320, 307, 292, 290, 223, 219, 210, 205, 182.5(++) [2]

1H NMR(CF3COOH): 4.20, 4.25, 4.55(each 3H, s, 3 × OCH3), 6.65(2H, s, CH2O2), 8.10, 8.35, 8.88, 8.94(each 1H, H–Ar) [2]

Pharm./Biol.: It has low toxicity. It prolongs the soporific action of chloral hydrate and hexobarbitalum [3]

References

  1. 1.
    Kh.G. Pulatova, Z.F. Ismailov, S.Yu. Yunusov, Chem. Nat. Comp. 2, 349 (1966)Google Scholar
  2. 2.
    F. Baralle, N. Schvarzberg, M.J. Vernengo, G.Y. Moltrasio, D. Giacopello, Phytochemistry 12, 948 (1973)Google Scholar
  3. 3.
    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 252Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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