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Lysicamine

Reference work entry

CAS Registry Number: 15444-20-9 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Liriodendron tulipiferum

C18H13NO3: 291.0895

Mp: 208–210°C (EtOH) [1]

UV: 235, 270, 307, 400(4.47, 4.41, 3.76, 3.94)

UV(H+): 249, 276, 306, 453(4.33, 4.44, 3.82, 5.55) [2]

IR: 1675 [2]

1H NMR: 3.95, 4.01(each 3H, s, 2×OCH3), 7.07(1H, s, H-3), 7.50(1H, dd, J = 7.5, 2.0, H-10), 7.70(1H, dd, J = 7.5, 2.0, H-9), 8.50(1H, dd, J = 7.5, 2.0, H-8), 9.05(1H, dd, J = 7.5, 2.0, H-11), 7.65, 8.77(each 1H, d, J = 5.5, H-4, H-5) [3,4]

13 C NMR: [ 4]

Table 1

C-1

145.3

C-4

123.4

C-9

128.7

1a

119.6

5

145.0

10

134.2

1b

122.0

6

156.7

11

128.3

2

152.0

7

182.5

11a

134.7

3

106.4

7a

132.0

1-OCH3

60.5

3a

135.3

8

128.7

2-OCH3

55.0

References

  1. 1.
    R. Ziyaev, A. Abdusamatov, S.Yu. Yunusov, Chem. Nat. Comp. 11, 495 (1975)Google Scholar
  2. 2.
    N. Katsui, K. Sato, S. Tobinaga, N. Takenchi, Tetrahedron Lett. 7, 6257 (1966)Google Scholar
  3. 3.
    H. Guinaudeau, M. Leboeuf, A. Cave, Lloydia 38, 275 (1975)Google Scholar
  4. 4.
    H. Guinaudeau, M. Leboeuf, A. Cave, J. Nat. Prod. 46, 761 (1983)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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