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Isocorydine

Reference work entry

CAS Registry Number: 475-67-2 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Argemone mexicana, Berberis densiflora, B. heteropoda, B. integerrima, B. nummularia, B. oblonga, B. thunbergii, B. turcomanica, B. vulgaris, Corydalis gortschakovii, C. ledebouriana, C. rosea-purpurea, Dicentra peregrina, Dicranostigma franschetianum, D. lactucoides, D. leptopodum, Eschscholtzia californica, Glaucium corniculatum, G. elegans, G. fimbrilligerum, G. flavum, G. oxylobum, Papaver commutatum, P. lisae, P. ocellatum

C20H23NO4: 341.1627

Mp: 183–184°C (EtOH) [1]

[α]D +181° (CHCl3) [1]

UV: 220, 267, 304 [1]

IR: 3400 [1]

MSm/z: 341(M+), 340, 326, 324, 310, 298, 283, 267, 170.5(++) [1]

1H NMR: 2.50(3H, s, NCH3), 3.68(3H, s, OCH3), 3.85(6H, s, 2×OCH3), 6.67(1H, s), 6.81(2H, s) [1]

13 C NMR: [ 2]

Table 1

C-1

141.7

C-4

29.1

C-10

149.0

1a

125.4

5

52.4

11

143.6

1b

129.8

6a

62.6

11a

119.8

2

150.8

7

References

  1. 1.
    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 386 (1996)Google Scholar
  2. 2.
    E. Wenkert, B.L. Buckwalter, I.R. Burfitt, M.J. Gasic, H.E. Gottlieb, E.W. Hagaman, F.M. Schell, P.M. Wovkulich, in Topics in C −13 NMR Spectroscopy, ed. by G.C. Levy, 2nd edn. (Wiley-Interscience, New York, 1976), p. 81Google Scholar
  3. 3.
    T.J. Betts, J. Chromatogr. 511, 373 (1990)Google Scholar
  4. 4.
    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 209Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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