Dicentrine (Eximine)

Reference work entry

CAS Registry Number: 517-66-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Dicentra peregrina

C20H21NO4: 339.1471

Mp: 158–159°C (MeOH) [1]

[α]D +57° (CHCl3) [1]

UV: 220, 282, 303 [1]

MSm/z: 339(M+), 338(100), 324, 307, 296, 281, 265 [1]

1H NMR: 2.25–3.25(7H, m), 2.45(3H, s, NCH3), 3.79(6H, s, 2×OCH3), 5.82, 5.96(each 1H, d, J = 2, CH2O2), 6.42, 6.70, 7.59(each 1H, s, 3×H–Ar) [1]

13 C NMR: [ 2]

Table 1

C-1

141.7

C-5

53.6

C-10

147.6

1a

116.6

6a

62.4

11

111.2

1b

126.4

7

34.3

11a

123.4

2

146.6

7a

128.3

NCH3

44.0

3

106.1

8

110.5

9-OCH3

55.9

3a

126.6

9

148.2

10-OCH3

56.1

4

29.2

       

References

  1. 1.
    I.A. Israilov, F.M. Melikov, D.A. Murav’eva, Chem. Nat. Comp. 20, 74 (1984)Google Scholar
  2. 2.
    H. Guinaudeau, M. Leboeuf, A. Cave, J. Nat. Prod. 42, 325 (1979)Google Scholar
  3. 3.
    H. Hara, F. Hashimoto, O. Hoshino, B. Umezawa, Chem. Pharm. Bull. 34, 1946 (1986)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations