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Corydine (Glaucentrine)

Reference work entry

CAS Registry Number: 476-69-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids – Aporphine Alkaloids

Biological sources: Aconitum leucostomum, A. orientale, Argemone hybrida, Corydalis gortschakovii, C. marschalliana, C. rosea-purpurea, Dicentra spectabilis, Dicranostigma franschetianum, Glaucium corniculatum, G. elegans, G. flavum, G. fimbrilligerum, G. oxylobum, G. squamigerum, Papaver croceum

C20H23NO4: 341.1627

Mp: 149–150°C [1]

[α]D + 204° (EtOH) [1]

UV: 218, 262, 270, 302 (4.19, 3.72, 3.70, 3.40) [1, 2]

IR(nujol): 3200, 1605, 1580, 1500, 1460, 1390, 1350, 1338, 1314, 1295, 1264, 1245, 1228, 1186, 1177, 1166, 1145, 1108, 1088, 1070, 1051, 1025, 995, 975, 961, 935, 900, 872, 855, 828, 820, 790, 770, 760, 730 [3]

MSm/z: 341(M+), 340, 326, 324, 310, 298, 283, 267, 170.5(++) [1]; 341(M+, 100), 326(60), 310(88), 298(14), 283(8) [2]

1H NMR: 2.54(3H, s, NCH3), 3.73(3H, s, OCH3), 3.85(6H, s, 2×OCH3), 6.70(1H, s, H-3),...

References

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    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 386 (1996)Google Scholar
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    M. Shamma, S.S. Salgar, Phytochemistry 12, 1505 (1973)Google Scholar
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    K.P. Tiwari, M. Masood, Phytochemistry 17, 1068 (1978)Google Scholar
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    D.S. Bhakuni, S. Tewari, M.M. Dhar, Phytochemistry 11, 1819 (1972)Google Scholar
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    H. Guinaudeau, M. Leboeuf, A. Cave, J. Nat. Prod. 57, 1033 (1994)Google Scholar
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    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 212Google Scholar

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© Springer Science+Business Media New York 2013

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