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N-Methyl-4-aminoquinolinium

Reference work entry

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Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Echinops albicaulis, E. chantavicus, E. karatavicus, E. ritro, E. maracandicus, E. sphaerocephalus

C10H11N2: 159.0922

[α]D + 54° [1]

Mp: 151°C (echinopsine), 314°C (echinopsidine) [1]

UV: 240, 310 (4.00, 3.50) [1]

IR(echinopsine): 1653, 1621, 1565, 1549, 1496 [1]

IR(echinopsidine): 3422, 3357, 3307, 3147, 1674, 1622, 1568, 1549, 1514 [1]

Pharm./Biol.(echinopsine): LD50 490 mg/kg (s/c, mice) [2]

Pharm./Biol.(echinopsidine): LD50 47.5 mg/kg (s/c, mice). Affects the peripheral and central links of the nervous system [2]

References

  1. 1.
    A.I. Ban’kovskii, M.E. Perel’son, V.A. Shevelev, DAN SSSR 148, 1073 (1963)Google Scholar
  2. 2.
    A.I. Leskov, Ya.S. Sokolov, Trudy VILAR 14, 79 (1971)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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