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Haplobine

Reference work entry

CAS Registry Number: 107783-37-9 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Haplophyllum obtusifolium

C18H18NO4Cl: 349.0895/347.0924

Mp: 151–153°C (Me2CO) [1]

UV: 251, 319, 330 (4.73, 3.60, 3.67) [1]

IR: 3145, 3115, 1628, 1588, 1518, 1495, 1460, 1390, 1370, 1323, 1270, 1235, 1150, 1100, 1089, 1060, 1000, 990 [2]

MSm/z: 349(6.2), 347(M+, 19), 312(4), 245(50), 244(100), 230(10), 227(43), 216(31), 199(9) [1]

1H NMR: 1.87(3H, s, CH3), 4.05(3H, s, OCH3), 4.09(2H, s, CH2Cl), 4.35(3H, s, OCH3), 4.78, 5.68(2H, d, 1H, t, J = 7, CH–CH2–O), 6.99, 7.53(each 1H, d, J = 2.8, H-3, H-2), 7.15, 7.93(each 1H, d, J = 9.4, H-6, H-5) [1]

References

  1. 1.
    I.A. Bessonova, S.Yu. Yunusov, Chem. Nat. Comp. 22, 684 (1986)Google Scholar
  2. 2.
    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 932 (1996)Google Scholar

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© Springer Science+Business Media New York 2013

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