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Folifidine

Reference work entry

CAS Registry Number: 3148-23-0 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Haplophyllum dubium, H. foliosum

C11H11NO3: 205.0739

Mp: 226–227°C (EtOH), 232°C (hydrochloride), 218°C (picrate), 151°C (Ac) [1]

Solubility: sol. alk. [1]

UV: 212, 225, 254, 288 sh, 332 (4.36, 4.38, 4.42, 3.78, 3.34) [2]

IR: 3300–2500, 1635 [2]

MSm/z: 205(M+, 100), 204(9), 190(18), 177(4), 176(9), 175(5), 174(4), 162(10) [3]

1H NMR(CF3COOH): 3.78, 3.98(each 3H, s, NCH3, OCH3), 6.27(1, s, H-3), 7.03(2H, m, H-7, H-6), 7.48(1H, dd, J = 8, 2.5, H-5) [4]

Pharm./Biol.: Estrogenic action [5]

References

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    Z.Sh. Faizutdinova, I.A. Bessonova, S.Yu. Yunusov, Chem. Nat. Comp. 3, 215 (1967)Google Scholar
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    V.I. Pastukhova, G.P. Sidyakin, S.Yu. Yunusov, Chem. Nat. Comp. 1, 20 (1965)Google Scholar
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    I.A. Bessonova, D. Batsuren, S.Yu. Yunusov, Chem. Nat. Comp. 20, 68 (1984)Google Scholar
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    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 932 (1996)Google Scholar
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    S.S. Nazrullaev, I.A. Bessonova, Kh.S. Akhmedkhodjaeva, Chem. Nat. Comp. 37, 551 (2001)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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