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Dubinidine

Reference work entry

CAS Registry Number: 22964-77-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Dictamnus angustifolius, Haplophyllum dubium, H. foliosum, H. perforatum

C15H17NO4: 275.1158

Mp: 132–133°C (Me2CO), ([α]D −63° (EtOH)); 196°C (hydrochloride), ([α]D −54° (MeOH)); 198°C (hydrobromide), 162°C (hydroiodide), ([α]D −47° (MeOH)); 177°C (nitrate), ([α]D −52° (MeOH)); 154°C (methiodide), 109°C (di Ac), ([α]D −48° (EtOH)); 215°C (isodubinidine), 83°C (dubinidinone), ([α]D +62° (CHCl3)); 186.5°C (Ac), ([α]D −57° (EtOH)) [1, 2, 3, 4]

UV: 230, 274, 284, 308, 320 (5.03, 4.31, 4.23, 4.08, 4.09) [1]

IR: 3400, 1630, 1595, 1540, 1438, 1375, 1180, 1062, 978, 948 [5]

MSm/z: 275(M+, 33), 245(4), 244(21), 226(12), 202(23), 201(55), 200(100), 188(4), 186(12), 185(13), 173(12), 172(12), 170(3), 158(8), 156(4), 143(4), 142(4), 130(4), 115(4), 75(5) [2]

1H NMR (Py-d5): 1.45(3H, s, CH3), 3.75, 5.05(2H, 1H, H-3, H-2), 3.95(3H,...

References

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