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Dictamnine

Reference work entry

CAS Registry Number: 484-29-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Dictamnus angustifolius, D. caucasicus, Haplophyllum bucharicum, H. bungei, H. dauricum, H. obtusifolium, H. perforatum, H. ramosissimum, H. robustum, Ruta graveolens

C12H9NO2: 199.0633

Mp: 132–133°C (Me2CO), 170°C (hydrochloride), 163°C (picrate), 188°C (isodictamine) [1]

UV: 212 sh, 233, 242 sh, 299 sh, 307, 334, 358 (4.42, 4.59, 4.50, 3.34, 3.94, 3.59, 3.57) [2]

IR: 3145, 3120, 1623, 1580, 1510, 1470, 1450, 1370, 1266 [2]

MSm/z: 199(M+, 100), 184(70), 156(33), 140(4), 128(26), 101(11), 76(7) [2]

1H NMR: 4.30(3H, s, OCH3), 6.90, 7.48(each 1H, d, J = 2.5, H-3, H-2), 7.20–8.00(3H, m, H–Ar), 8.10(1H, dd, J = 8.2, 2, H-5) [2]

13 C NMR: [ 3]

Table 1

C-2

143.6

C-4

122.4

C-7

129.6

 2a

 4a

 8

127.9

 3

104.7

 5

122.4

 8a

 3a

 6

123.7

4-OCH3

59.0

References

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    N.M.D. Brown, M.F. Grundon, D.M. Harrison, S.A. Surgenor, Tetrahedron 36, 3579 (1980)Google Scholar
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    H. Kanamori, I. Sakamoto, M. Mizuta, Chem. Pharm. Bull. 34, 1826 (1986)Google Scholar
  5. 5.
    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 269Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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