Advertisement

Choisyine

Reference work entry

CAS Registry Number: 18556-07-5 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Choisya ternata

C18H19NO5: 329.1263

Mp: 188–189°C (EtOH), 145°C (nitrate), 196°C (sulphate), 191°C (perchlorate), 210°C (picrolonate), 177°C (hydrochloride), 252°C (picrate), 232°C (Ac), 259°C (isochoisyine), 256°C (norchoisyine) [1, 2, 3]

Solubility: sol. EtOH, CHCl3, C6H6 [1, 2, 3]

UV: 255, 320, 330, 351 [1]

IR: 3405, 1627 [1]

MSm/z: 329(M+, 79), 311(6), 296(54), 270(100), 256(14), 255(12), 241(10), 240(10), 228(13), 226(26) [3]

1H NMR: 1.29, 1.42(each 3H, s, 2 × CH3), 3.70, 4.77(2H, 1H, H-10, H-9), 3.91, 4.29(each 3H, s, 2 × OCH3), 6.95, 7.50(each 1H, d, J = 2, 5, H-3, H-2), 7.13(1H, s, H-8) [3]

13 C NMR [ 4]:

Table 1

C-2

142.6

C-5

C-10

33.9

 2a

 6

 11

72.0

 3

104.6

 7

 12

24.4

 3a

 8

106.8

 13

26.1

 4

 8a

4-OCH3

58.9

 4a

 9

90.7

7-OCH3

55.8

References

  1. 1.
    V.I. Frolova, A.I. Ban’kovskii, M.V. Volynskaya, Med. Prom. SSSR (7), 35 (1958)Google Scholar
  2. 2.
    V.L. Frolova, A.D. Kuzovkov, Zh. Obshch. Khim. 33, 121 (1963)Google Scholar
  3. 3.
    S.R. Johns, J.A. Lamberton, A.A. Sioumis, Austral. J. Chem. 20, 1975 (1967)Google Scholar
  4. 4.
    N.M.D. Brown, M.F. Grundon, D.M. Harrison, S.A. Surgenor, Tetrahedron 36, 3579 (1980)Google Scholar
  5. 5.
    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 276Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations