Bucharidine

Reference work entry

CAS Registry Number: 25865-94-5 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Haplophyllum bucharicum

C19H25NO4: 331.1783

Mp: 251–252°C (Me2CO) [1]

[α]D 0° (Py) [1]

Solubility: sol. CHCl3 [1]

UV: 214, 228, 265 sh, 274, 282, 306 sh, 314, 328 (4.36, 4.43, 3.54, 3.72, 3.76, 3.43, 3.77, 3.66) [1]

IR: 3470, 1643, 1608, 1500, 1425, 1380, 1335, 1310, 1280, 1190, 1160, 1120, 1060, 1040, 890 [2]

MSm/z: 331(M+, 3), 316(6), 272(18), 214(9), 189(38), 188(25), 174(8), 162(4), 143(100), 125(31), 85(22), 71(39), 59(6) [3]

1H NMR: 1.16(6H, s, 2 × CH3), 1.23(3H, d, J = 6.5, CH3), 1.30(3H, s, CH3), 1.70–2.30(4H, m, CH2–CH2), 3.70–4.10(2H, m, Ar–CH, CH–O), 7.22(3H, m, H–Ar), 7.88(1H, d, J = 8.5, H-5) [1]

Pharm./Biol.: Estrogenic action [4]

References

  1. 1.
    Z.Sh. Faizutdinova, I.A. Bessonova, Ya.V. Rashkes, S.Yu. Yunusov, Chem. Nat. Comp. 6, 232 (1970)Google Scholar
  2. 2.
    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 216 (1996)Google Scholar
  3. 3.
    Ya.V. Rashkes, Z.Sh. Faizutdinova, I.A. Bessonova, S.Yu. Yunusov, Chem. Nat. Comp. 6, 593 (1970)Google Scholar
  4. 4.
    S.S. Nazrullaev, I.A. Bessonova, Kh.S. Akhmedkhodjaeva, Chem. Nat. Comp. 37, 551 (2001)Google Scholar

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