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Acutine

Reference work entry

CAS Registry Number: 36150-05-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinoline Alkaloids

Biological sources: Haplophyllum acutifolium

C16H19NO: 241.1467

Mp: 122–123°C (Me2CO), 143°C (dihydro) [1]

Solubility: sol. CHCl3, EtOH, MeOH; insol. Et2O, petr. ether, H2O [1]

UV: 214, 235, 305 sh, 318, 330 (4.45, 4.61, 3.92, 4.04, 3.97) [1]

IR: 1635, 1597, 1560, 1510 [1]

MSm/z: 241(M+, 16), 226, 212, 199, 186, 173(24), 172(39), 159(100), 130(12) [1]

1H NMR: 0.84(3H, t, J = 7, CH3), 1.87(6H, m, CH2), 2.68(2H, t, J = 7, Ar–CH2), 5.12(2H, m, CH = CH), 6.21(1H, s, H-3), 7.25–7.90(3H, m, H–Ar), 8.24(1H, d, J = 9, H-5) [1]

Pharm./Biol.: Estrogenic action [2]

References

  1. 1.
    D.M. Razakova, I.A. Bessonova, S.Yu. Yunusov, Chem. Nat. Comp. 9, 199 (1973)Google Scholar
  2. 2.
    S.S. Nazrullaev, I.A. Bessonova, Kh.S. Akhmedkhodjaeva, Chem. Nat. Comp. 37, 551 (2001)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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