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Kudzusaponin A3

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – Kudzusapogenol A

Biological source: Pueraria lobata [1], Abrus cantoniensis [2], Russell lupine [3]

C48H78O20: 974.508

[α]D25-3.4° (c 0.68, C5H5N:H2O 1:1) [1]

FAB-MS (positive ion mode) m/z: 998.4990 (M + Na)+, 975 (M + H)+, 829 (M + H-Rha)+, 667 (M + H-Rha-Gal)+ [1]

1H NMR (270 MHz, J/Hz, C5D5N): 0.69, 0.95, 1.30, 1.30, 1.34, 1.50 (s, CH3 × 6), 5.33 (s, H-12)

α-L-Rhap: 6.27 (s, H-1), 1.77 (d, J = 6.0, CH3-6)

β-D-GlcUAp: 4.96 (d, J = 6.0, H-1)

β-D-Galp: 5.78 (d, J = 7.0, H-1) [1]

13 C NMR (C 5D 5N): [ 1]

Table 1

C-1

38.4

C-16

27.3

GlcUA-1

105.3

Rha-1

102.3

2

26.5

17

38.9

2

78.3

2

72.3

3

91.0

18

43.1

3

76.6

3

72.7

4

43.8

19

40.9

4

73.7

4

74.3

5

55.9

20

40.9

5

77.7

5

69.3

6

18.4

21

70.3

6

171.1

6

18.9

7

32.8

22

79.7

Gal-1

101.6

   

8

40.1

23

22.9

2

77.5

   

9

47.6

24

63.5

3

76.3

   

10

36.3

25

15.7

4

71.0

   

11

24.0

26

16.7

5

76.5

   

12

122.3...

References

  1. 1.
    T. Arao, J. Kinjo, T. Nohara, R. Isobe, Chem. Pharm. Bull. 45(2), 362 (1997)CrossRefGoogle Scholar
  2. 2.
    H. Miyao, Y. Sakai, T. Takeshita, J. Kinjo, T. Nohara, Chem. Pharm. Bull. 44, 1222 (1996)CrossRefGoogle Scholar
  3. 3.
    J. Kinjo, F. Kishida, K. Watanabe, F. Hashimoto, T. Nohara, Chem. Pharm. Bull. 42, 1874 (1994)CrossRefGoogle Scholar

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© Springer Science+Business Media New York 2013

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