Advertisement

Licorice-Saponin A3

Reference work entry

CAS Registry Number: 118325-22-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – Glycyrrhetic Acid

Biological source: Glycyrrhiza uralensis [1], G. inflata [2]

C48H72O21: 984.456

Mp: 196–199°C (MeOH-H2O) [1]

[α]D23 + 69.0° (c 1.1, MeOH) [1]

UV λmaxMeOH nm (ε): 249 (8800) [1]

IR (KBr) νmax cm−1: 3360, 3000–2500 (br), 1741, 1716, 1650, 1041 [1]

1H NMR (500 MHz, J/Hz, C5D5N + D2O): 0.89, 1.01, 1.19, 1.21, 1.25, 1.34, 1.38 (s, CH3 × 7), 3.00 (brd, J = 13.0, H-18), 3.35 (dd, J = 4.7, 11.8, H-3), 5.92 (s, H-12)

β-D-GlcUAp: 5.01 (d, J = 7.6, H-1)

β-D-GlcUAp′: 5.36 (d, J = 7.8, H-1)

β-D-Glcp: 6.30 (d, J = 8.2, H-1) [1]

13 C NMR (22.5 MHz, C 5D 5N ): [ 1]

Table 1

C-3

89.0

GlcUA-1

104.5

11

199.3

6

171.6

12

128.4

GlcUA′-1

106.2

13

168.0

6

172.0

18

47.9

Glc-1

95.5

22

37.6

6

62.5

30

175.3

   

References

  1. 1.
    I. Kitagawa, K. Hori, T. Taniyama, J.-L. Zhou, M. Yoshikawa, Chem. Pharm. Bull. 41(1), 43 (1993)CrossRefGoogle Scholar
  2. 2.
    I. Kitagawa, J.-L. Zhou, M. Sakagami, T. Taniyama, M. Yoshikawa, Chem. Pharm. Bull. 36, 3710 (1988)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations