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Licorice-Saponin E2

Reference work entry

CAS Registry Number: 119418-01-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – Glabrolide

Biological source: Glycyrrhiza uralensis [1]

C42H60O16: 820.388

Mp: 218–219°C (MeOH) [1]

[α]D20 + 68.0° (c 0.2, MeOH) [1]

UV λmaxMeOH nm (ε): 250 (12700) [1]

IR (KBr) νmax cm−1: 3400–3000 (br), 2929, 1780, 1724, 1645, 1385, 1010 [1]

1H NMR (500 MHz, J/Hz, C5D5N-D2O): 0.79, 1.06, 1.21, 1.22, 1.34, 1.40, 1.42 (s, CH3 × 7), 3.02 (brd, J = 12, H-18), 3.35 (dd, J = 4.4, 11.2, H-3), 5.94 (s, H-12)

β-D-GlcUAp: 5.02 (d, J = 7.6, H-1)

β-D-GlcUAp′: 5.38 (d, J = 7.6, H-1) [1]

13 C NMR (22.5 MHz, C 5D 5N): [ 1]

Table 1

C-3

89.0

GlcUA-1

104.6

GlcUA′-1

106.2

11

198.8

2

83.8

2

76.1

12

129.6

3

76.2

3

77.2

13

164.3

4

72.2

4

72.5

18

44.8

5

77.2

5

77.2

22

84.0

6

169.7

6

169.8

24

16.4

       

29

28.0

       

30

179.3

       

References

  1. 1.
    I. Kitagawa, K. Hori, M. Sakagami, J.-L. Zhou, M. Yoshikawa, Chem. Pharm. Bull. 41(8), 1337 (1993)CrossRefGoogle Scholar

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