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Licorice-Saponin F3

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – Deoxoglabrolide

Biological source: Glycyrrhiza uralensis [1, 2]

C48H72O19: 952.466

Mp: 215–217°C [1]

[α]D20 −20° (c 0.1, MeOH) [1]

IR (KBr) νmax cm−1: 3400, 1760, 1720 [1]

FAB-MSm/z: 1003 (M + Na)+[1]

1H NMR (500 MHz, J/Hz, C5D5N): 0.71, 0.75, 1.11, 1.14 (CH3 × 4), 1.26 (CH3 × 2), 3.27 (dd, J = 4.4, 10.8, Hα-3), 5.40 (H-12), 5.36 (d, J = 7.6, H-1 of GlcUA), 5.68 (d, J = 6.9, H-1 of GlcUA′), 6.10 (brs, H-1 of Rha) [1]

13 C NMR (22.5 MHz, C 5D 5N) (for methyl derivate): [ 1]

Table 1

C-3

89.9

GlcUA-1

104.7

Rha-1

101.6

11

47.5

2

79.1

2

71.8

12

124.8

3

76.3

3

72.8

13

140.6

4

72.2

4

73.9

18

47.5

5

77.9

5

69.1

22

84.3

6

170.1

6

18.5

24

16.3

GlcUA′-1

102.4

   

29

28.0

2

78.2

   

30

180.1

3

76.6

   
   

4

72.8

   
   

5

77.6

   
   

6

169.8

   

References

  1. 1.
    I. Kitagawa, J.L. Zhou, M. Sakagami, E. Uchida, M. Yoshikawa, Chem. Pharm. Bull. 39(1), 244 (1991)CrossRefGoogle Scholar
  2. 2.
    I. Kitagawa, K. Hori, M. Sakagami, J.L. Zhou, M. Yoshikawa, Chem. Pharm. Bull. 41(8), 1337 (1993)CrossRefGoogle Scholar

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