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Kochianoside I

Reference work entry

CAS Registry Number: 193894-08-5 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – 22α-Hydroxy-oleanolic Acid

Biological source: Kochia scoparia [1]

C36H56O10: 648.387

Mp: 172–175°C (CHCl3−MeOH) [1]

[α]D24 + 84.4° (c 0.1, MeOH) [1]

IR (KBr) νmax cm−1: 3432, 2932, 2876, 1726, 1701, 1665, 1081 [1]

FAB-MS (negative ion mode) m/z: 647 (M-H), 471 (M-C6H9O6) [1]

FAB-MS (positive ion mode) m/z: 671.3772 (M + Na)+ [1]

1H NMR (J/Hz, C5D5N): 0.82, 0.98, 1.02, 1.02, 1.12, 1.31, 1.36 (s, CH3-25, 24, 26, 29, 30, 23, 27), 3.34 (m, H-18), 3.40 (dd, J = 4.6, 11.9, H-3), 4.53 (dd, J = 4.6, 10.7, H-22), 5.46 (brs, H-12)

β-D-GlcUAp: 5.01 (d, J = 7.7, H-1) [1]

13 C NMR (125 MHz, C 5D 5N): [ 1]

Table 1

C-1

38.7

C-16

17.0

GlcUA-1

107.2

2

26.6

17

53.1

2

75.6

3

89.1

18

43.5

3

78.2

4

39.6

19

46.1

4

73.4

5

55.8

20

31.5

5

77.8

6

18.5

21

43.3

6

172.7

7

33.1

22

71.5

   

8

40.0

23

28.3

   

9

48.0

24

17.0

   

10

37.0

25...

References

  1. 1.
    M. Yoshikawa, Y. Dai, H. Shimada, T. Morikawa, N. Matsumura, S. Yoshizumi, H. Matsuda, H. Matsuda, M. Kubo, Chem. Pharm. Bull. 45(6), 1052 (1997)CrossRefGoogle Scholar

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© Springer Science+Business Media New York 2013

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