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Scrophulasaponin III

Reference work entry

CAS Registry Number: 155762-35-9 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – 3β,21α,23,28-Tetrahydroxy-olean-11,13(18)-diene

Biological source: Scrophularia kakudensis [1]

C54H88O22: 1088.576

[α]D25−9.7° (c 0.98, MeOH) [1]

FAB-MSm/z: 1112 [M + Na]+ [1]

1H NMR (500 MHz, J/Hz, C5D5N): 4.17 (dd, J = 12.0, 5.0, H-3), 5.72 (brd, J = 10.0, H-11), 6.65 (brd, J = 10.0, H-12), 3.72, 4.38 (d, J = 11.0, H2-23), 0.83, 0.98, 1.05, 1.07, 1.11, 1.29 (CH3 × 6)

β-D-Fucp: 4.94 (d, J = 8.0, H-1), 4.66 (brt, J = 8.5, H-2), 4.08 (dd, J = 9.0, 3.0, H-3), 4.16 (H-4), 3.63 (m, H-5), 1.42 (d, J = 6.5, CH3-6)

β-D-Glcp: 5.58 (d, J = 8.0, H-1)

β-D-Glcp′: 5.25 (d, J = 8.0, H-1), 3.92 (t, J = 8.5, H-2), 4.16 (t, J = 8.5, H-3), 4.37 (t, J = 9.0, H-4), 3.75 (m, H-5), 4.10, 4.18 (H2-6)

α-L-Rhap: 5.82 (brs, H-1), 1.73 (d, J = 6.5, CH3-6) [1]

13 C NMR (67.80 MHz, C 5D 5N): [ 1]

Table 1

C-1

38.4

C-16

24.6

Fuc-1

104.2

Glc′-1...

References

  1. 1.
    A. Yamamoto, T. Miyase, A. Ueno, T. Maeda, Chem. Pharm. Bull. 41(10), 1780 (1993)CrossRefGoogle Scholar

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