Centellasaponin D

Reference work entry

CAS Registry Number: 386223-77-4 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Oleanene Type – 3β,6β,23-Trihydroxy-olean-12-en-28-oic Acid

Biological source: Centella asiatica [1]

C48H78O19: 958.513

Mp: 202–203°C [1]

[α]D25 − 12.4° (c 0.3, MeOH) [1]

IR (KBr) νmax cm−1: 3432, 2932, 1739, 1655, 1062 [1]

FAB-MSm/z: 981.5035 [M + Na]+; 957 [M-H]−, 811 [M-C6H11O4], 487 [M-C18H31O14] [1]

1H NMR (500 MHz, J/Hz, C5D5N): 0.88, 0.90, 1.21, 1.68, 1.69, 1.71 (s, CH3 × 6), 3.21 (dd, J = 4.6, 13.7, H-18), 4.00, 4.34 (d, J = 10.3, H2-23), 4.20 (m, H-3), 4.99 (brs, H-6), 5.52 (dd, J = 3.4, 3.6, H-12)

β-D-Glcp: 6.15 (d, J = 8.2, H-1)

β-D-Glcp′: 4.94 (d, J = 7.9, H-1)

α-L-Rhap: 5.77 (brs, H-1), 1.66 (d, J = 6.1, CH3-6) [1]

13 C NMR (125 MHz, C 5D 5N): [ 1]

Table 1

C-1

41.3

C-16

23.6

Glc-1

95.8

Rha-1

102.7

2

28.0

17

47.1

2

73.9

2

72.5

3

73.6

18

41.8

3

78.5

3

72.7

4

44.0

19

46.4

4

71.1

4

74.0

5

49.6

20

30.8

5

77.9

5

70.3...

References

  1. 1.
    H. Matsuda, T. Morikawa, H. Ueda, M. Yoshikawa, Chem. Pharm. Bull. 49(10), 1368 (2001)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations