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Ginsenoside La

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Dammarane Type – Protopanaxadiol-12,23-oxid

Biological source: Panax ginseng [1]

C42H68O13: 780.465

Mp: 179–180°C (MeOH) [1]

[α]D − 18.4° (C5N5N) [1]

FAB-MSm/z: 781 [M-H] [1]

IR (KBr) νmax cm−1: 3500 [1]

1H NMR (J/Hz): 3.64 (d, J = 8, H-12), 0.95 (s, CH3-18), 0.83 (s, CH3-19), 1.50 (s, CH3-21), 4.81 (t, J = 9, H-23), 5.51 (brd, J = 9, H-24), 1.66 (s, CH3-26), 1.80 (s, CH3-27), 1.30 (s, CH3-28), 1.00 (s, CH3-29), 1.06 (s, CH3-30)

β-D-Glcp: 4.94 (d, J = 8, H-1), 4.04 (t, J = 8, H-2), 4.26 (m, H-3), 4.22 (m, H-4), 4.02 (m, H-5), 4.40 (dd, J = 11, 5, H-6), 4.60 (dd, J = 11, 2, H-6)

β-D-Glcp′: 5.13 (d, J = 8, H-1), 3.97 (t, J = 8, H-2), 4.26 (m, H-3), 4.23 (m, H-4), 3.98 (m, H-5), 4.36 (dd, J = 11, 2, H-6), 4.54 (dd, J = 11, 5, H-6) [1]

13 C NMR (C 5D 5N): [ 1]

Table 1

C-1

39.4

C-12

79.8

Glc-1

106.9

3

88.7

13

49.7

2

75.8

4

39.7

14

51.2

3

78.8

5

56.4

15

32.5

4

71.89...

References

  1. 1.
    S. Zhang, X. Yao, Y. Chen, C. Cui, Y. Tezuka, T. Kikuchi, Chem. Pharm. Bull. 37(7), 1966 (1989)CrossRefGoogle Scholar

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