Gymnemaside VII

CAS Registry Number: 141380-42-9

Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Dammarane Type – 25-Hydroperoxy-dammar-23-en-2α,3β,12β,20(S)-tetraol

Biological source: Gymnema sylvestre [1]

C₄₁H₇₀O₁₅: 802.471

Mp: 185–187°C [1]

[α]_D −7.7° (C 1.4, MeOH) [1]

FAB-MS m/z: 826 [M + Na + H]⁺ [1]

¹ H NMR (400 MHz, J/Hz, C₅D₅N): 0.87, 0.99, 1.04, 1.09, 1.26, 1.61, 1.67, 1.62, (s, CH₃ × 7), 3.40 (dd, J = 11.5, 4.0, H-3), 6.13 (d, J = 15.5, H-24), 6.20 (ddd, J = 15.5, 8.0, 4.5, H-23), 4.96 (d, J = 7.5, H-1 of Xyl), 5.16 (d, J = 8.0, H-1 of Glc) [1]

¹³ C NMR (100 MHz, C₅D₅N): [1]

Table 1

C-1	48.4	C-11	30.6	C-21	23.1	Glc-1	98.2	Xyl-1	105.6
2	68.8	12	70.3	22	38.0	2	75.0	2	74.8
3	83.7	13	49.7	23	126.8	3	79.0	3	78.0
4	40.0	14	51.5	24	140.1	4	71.6	4	71.1
5	56.5	15	31.1	25	81.4	5	76.8	5	67.0
6	18.8	16	26.4	26	25.1	6	70.0
7	35.1	17	51.8	27	25.4
8	40.2	18	16.1	28	29.2
9	50.3	19	17.3	29	17.6
10	38.6	20	83.2	30	17.5