Notoginsenoside I

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Dammarane Type – 3β,20(S)-Dihydroxy-dammar-24-ene

Biological source: Panax notoginseng [1]

C54H92O22: 1092.608

Mp: 209–211°C (aq. MeOH) [1]

[α]D24 + 0.8° (c 0.1, MeOH) [1]

IR (KBr) νmax cm−1: 3410, 1637, 1078 [1]

FAB-MS (negative ion mode) m/z: 1091 (M-H), 929 (M-C6H11O5), 767 (M-C12H21O10) [1]

FAB-MS (positive ion mode) m/z: 1115.5968 (M + Na)+ [1]

1H NMR (J/Hz, C5D5N): 0.81, 0.98, 0.99, 1.12, 1.28, 1.53 (s, CH3-19, 30, 18, 29, 28, 21), 1.72 (CH3-26, 27), 3.23 (dd, J = 4.0, 11.3, H-3), 5.40 (brs, H-24)

β-D-Glcp: 4.88 (d, J = 7.6, H-1); β-D-Glcp′: 5.34 (d, J = 7.6, H-1); β-D-Glcp″: 5.22 (d, J = 7.6, H-1); β-D-Glcp″′: 5.09 (d, J = 7.6, H-1) [1]

13 C NMR (125 MHz, C 5D 5N): [ 1]

Table 1

C-1

39.3

C-18

15.7

Glc-1

105.0

Glc″-1

98.6

2

26.1

19

16.4

2

83.2

2

75.4

3

89.0

20

82.4

3

78.2

3

78.8

4

39.7

21

21.3

4

71.7

4

71.5

5

56.3

22

40.4

5

78.0

5

76.7

6

18.4

23

23.2...

References

  1. 1.
    M. Yoshikawa, T. Murakami, T. Ueno, N. Hirokawa, K. Yashiro, N. Murakami, J. Yamahara, H. Matsuda, R. Saijoh, O. Tanaka, Chem. Pharm. Bull. 45(6), 1056 (1997)CrossRefGoogle Scholar

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© Springer Science+Business Media New York 2013

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