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Notoginsenoside H

Reference work entry

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Dammarane Type – 3β,7β,12β,20(S)-Tetrahydroxy-dammar-5,24-diene

Biological source: Panax notoginseng [1]

C47H80O19: 948.529

Mp: 201–203°C (aq. MeOH) [1]

[α]D25 + 14.9° (c 0.1, MeOH) [1]

IR (KBr) νmax cm−1: 3410, 1647, 1078 [1]

FAB-MS (negative ion mode) m/z: 947.5192 (M-H) [1]

FAB-MS (positive ion mode) m/z: 971 (M + Na)+ [1]

1H NMR (J/Hz, C5D5N): 0.73, 0.99, 1.19, 1.48, 1.55, 2.08 (s, CH3-30, 19, 18, 29, 26, 28), 1.56 (s, CH3-21, 27), 3.50 (dd, J = 3.7, 10.4, H-3), 4.35 (m, H-6), 5.76 (brs, H-12), 6.04 (d, J = 15.6, H-24), 6.30 (ddd-like, H-23)

β-D-Glcp: 4.93 (d, J = 7.3, H-1); β-D-Xylp: 5.77 (d, J = 7.9, H-1); β-D-Glcp′: 5.19 (d, J = 7.3, H-1) [1]

13 C NMR (125 MHz, C 5D 5N): [ 1]

Table 1

C-1

39.4

C-18

17.5

Glc-1

103.4

2

27.8

19

17.6

2

80.1

3

78.8

20

83.2

3

79.8

4

40.2

21

23.1

4

71.7

5

61.3

22

39.1

5

78.0

6

79.5

23

122.7

6

62.8

7

44.8

24

142.1

Xyl-1

104.8...

References

  1. 1.
    M. Yoshikawa, T. Murakami, T. Ueno, N. Hirokawa, K. Yashiro, N. Murakami, J. Yamahara, H. Matsuda, R. Saijoh, O. Tanaka, Chem. Pharm. Bull. 45(6), 1056 (1997)CrossRefGoogle Scholar

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© Springer Science+Business Media New York 2013

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