Ginsenoside-Rh5

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Taxonomy: Physicochemical and Pharmacological Properties of Triterpene Glycosides – Glycosides of Aglycones of Dammarane Type – 3β,6α,12β,24ξ-Tetrahydroxy-dammar-20(22),25-diene

Biological source: Panax ginseng [1]

C36H60O9: 636.423

[α]D21 + 20.8° (c 0.1, MeOH) [1]

HR-FAB-MSm/z: 659.4135 [M + Na]+ [1]

1H NMR (500 MHz, J/Hz, C5D5N): 0.84, 1.06, 1.24, 1.62, 1.83, 1.88, 2.09 (s, CH3-30, 19, 18, 29, 21, 27, 28), 2.41, 2.55 (m, H-23), 3.54 (dd, J = 5.0, 11.5, H-3), 3.95 (m, H-12), 4.37 (dd, J = 3.5, 8.5, H-24), 4.47 (dd, J = 3.0, 10.5, H-6), 5.28, 4.98 (brs, H2-26), 5.69 (t-like, J = 7.5, H-22)

β-D-Glcp: 5.05 (d, J = 8.0, H-1), 4.12 (t, J = 8.0, H-2), 4.27 (t-like, J = 8.5, H-3), 4.23 (dd, J = 8.5, H-4), 4.39 (dd, J = 5.5, 11.0, H-6), 4.56 (dd, J = 2.5, 12.0, H-6) [1]

13 C NMR (C 5D 5N): [ 1]

Table 1

C-1

39.5

C-16

26.8

Glc-1

106.1

2

28.0

17

51.0

2

75.5

3

78.6

18

17.4

3

79.7

4

40.2

19

17.7

4

71.9

5

61.5

20

142.4

5

78.2

6

80.1

21

13.2

6

63.1

7

45.4

22

122.2

   

8

41.4

23

35.3...

References

  1. 1.
    D.-Q. Dou, Y.-J. Chen, L.-H. Liang, F.-G. Pang, F.-G. Pang, N. Shimizu, T. Takeda, Chem. Pharm. Bull. 49(4), 442 (2001)CrossRefGoogle Scholar

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