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Protein Structure Metapredictors

  • Reference work entry
Encyclopedia of Systems Biology

Synonyms

Backbone or carbon-α chain (both with the sidechain); Prediction methods; Predictors: prediction tools; Primary structure: amino acid sequence; Protein sequence; Secondary structure 2D structure; Tertiary structure, 3D structure; α-helix, β-sheet, loop carbon-alpha positioning

Definition

Protein Structures

Proteins are biological compounds composed of a long chain of amino acids, connected to each other through their carbon-alpha atoms and have a 3D shape resulting from the protein folding process. Proteins are usually described by means of four structures (Lesk 2001): the primary structure, the secondary structure, the tertiary structure and the quaternary structure. Each structure captures a particular conformational property of the protein and helps understand its behavior.

Primary Structure

The primary structure of a protein identifies its amino acid sequence. The sequence is determined in the cell during the translation phase, where nucleotide triplets are read from the...

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Author information

Authors and Affiliations

  1. Dipartimento di Elettronica, Informatica e Sistemistica, Università della Calabria, Via Pietro Bucci 42C, Rende, 87036, Italy

    Prof. Luigi Palopoli & Dr. Simona E. Rombo

  2. Dipartimento di Matematica, Università della Calabria, Via Pietro Bucci 32B, Rende, 87036, Italy

    Dr. Giorgio Terracina

  3. Department of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Campus S. Venuta viale Europa, Catanzaro, 88100, Italy

    Giuseppe Tradigo

  4. Istituto di Calcolo e Reti ad Alte Prestazioni, Consiglio Nazionale delle Ricerche, Via Pietro Bucci 41C, Rende (CS), 87036, Italy

    Dr. Simona E. Rombo

  5. Department of Medical and Surgical Sciences, University Magna Græcia of Catanzaro, Catanzaro, Italy

    Dr. Pierangelo Veltri

Authors
  1. Prof. Luigi Palopoli
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  2. Dr. Simona E. Rombo
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  3. Dr. Giorgio Terracina
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  4. Giuseppe Tradigo
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  5. Dr. Pierangelo Veltri
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Corresponding author

Correspondence to Luigi Palopoli .

Editor information

Editors and Affiliations

  1. Biomedical Sciences Research Institute, University of Ulster, Coleraine, UK

    Werner Dubitzky

  2. Department of Computer Science, University of Rostock, Rostock, Germany

    Olaf Wolkenhauer

  3. Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea

    Kwang-Hyun Cho

  4. Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

    Hiroki Yokota

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Palopoli, L., Rombo, S.E., Terracina, G., Tradigo, G., Veltri, P. (2013). Protein Structure Metapredictors. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_991

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