Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Protein Structure Metapredictors

  • Luigi Palopoli
  • Simona E. Rombo
  • Giorgio Terracina
  • Giuseppe Tradigo
  • Pierangelo Veltri
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_991



Protein Structures

Proteins are biological compounds composed of a long chain of amino acids, connected to each other through their carbon-alpha atoms and have a 3D shape resulting from the protein folding process. Proteins are usually described by means of four structures (Lesk 2001): the primary structure, the secondary structure, the tertiary structure and the quaternary structure. Each structure captures a particular conformational property of the protein and helps understand its behavior.

Primary Structure

The primary structure of a protein identifies its amino acid sequence. The sequence is determined in the cell during the translation phase, where nucleotide triplets are read...

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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Luigi Palopoli
    • 1
  • Simona E. Rombo
    • 4
    • 1
  • Giorgio Terracina
    • 2
  • Giuseppe Tradigo
    • 3
  • Pierangelo Veltri
    • 5
  1. 1.Dipartimento di ElettronicaInformatica e Sistemistica, Università della CalabriaRendeItaly
  2. 2.Dipartimento di MatematicaUniversità della CalabriaRendeItaly
  3. 3.Department of Experimental and Clinical MedicineUniversity Magna Græcia of CatanzaroCatanzaroItaly
  4. 4.Istituto di Calcolo e Reti ad Alte PrestazioniConsiglio Nazionale delle RicercheRende (CS)Italy
  5. 5.Department of Medical and Surgical SciencesUniversity Magna Græcia of CatanzaroCatanzaroItaly