Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Protein Contact Maps

  • Giuseppe TradigoEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_980



Predicting the tertiary structure of a protein by looking at its amino acid (i.e., primary) sequence is usually called the protein folding problem. Contact map structures are bidimensional objects representing some of the structural information of a protein. In this contribution, we treat the use of contact map predictions to improve the quality of the predicted tertiary structure.

Protein Structure

Proteins are macromolecules involved in many important biological mechanisms of the living organisms, such as providing structures (ligaments, fingernails, hair), helping in digestion (stomach enzymes), aiding in movement (muscles). They are composed of a long chain of amino acids. Protein structures represents the spatial conformation and properties useful to understand its behavior.

Protein Structure Prediction

Protein structure prediction is a key topic in computational structural proteomics. Structure prediction is a...

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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of Experimental and Clinical MedicineUniversity Magna Græcia of CatanzaroCatanzaroItaly