Definition
The whole set of protein interactions in a cell is often modeled by using graphs. Usually these graphs are referred to as Protein Interaction Networks. Currently, there is a large number of laboratories that are producing data about protein interaction networks as well as a large number of laboratories that mine these data to extract biologically relevant knowledge. In this scenario, the distributed analysis of protein interaction networks is a set of complex activities that can be structured on: (1) the Sharing and dissemination of PPI data among different databases; (2) the collection of data stored in heterogeneous databases; and (3) the Distributed analysis based on distributed and high-performance infrastructures.
Characteristics
Information representable as a network is mostly modeled using graph theory Lesne (2006). Informally, a graph is a structure composed of a set of nodes and edges linking them. A graph G is defined as G = {V, E}, where V is a set of nodes, Eis...
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References
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Guzzi, P.H. (2013). Protein–Protein Interaction Networks, Distributed Analysis. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_970
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DOI: https://doi.org/10.1007/978-1-4419-9863-7_970
Publisher Name: Springer, New York, NY
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