Skip to main content

Constraint

  • Reference work entry
Encyclopedia of Systems Biology

Synonyms

(Approx.) boundary condition; Control

Definition

Constraint refers to a reduction of the degrees of freedom of the elements of a system exerted by some collection of elements, or a limitation or bias on the variability or possibilities of change in the kind of such elements.

Although the term has several meanings in diverse scientific fields, the idea of a constraint is usually employed in relation to conceptualizations in terms of levels or hierarchies. Some general features of constraints such understood are the following: constraints do not interact with the elements they influence and their dynamics; they arise from dynamics at different levels of organization; constraint relations are always asymmetric, and may give rise to new phenomena.

In the tradition of the theories of emergent evolution of the early twentieth century and, even clearer, in the theory of levels of integration of the organicist tradition of the 1930s, higher levels are understood as arising from...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 899.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Allen TFH, Starr TB (1982) Hierarchy. Perspectives for ecological complexity. The University of Chicago Press, Chicago

    Google Scholar 

  • Amundson R (1994) Two concepts of constraint: adaptationism and the challenge from developmental biology. Philos Sci 61:556–578

    Google Scholar 

  • Blitz D (1992) Emergent evolution. Qualitative novelty and the levels of reality. Kluwer, Dordrecht

    Google Scholar 

  • Kauffman S (2000) Investigations. Oxford University Press, Oxford

    Google Scholar 

  • Kauffman S (2003) Molecular autonomous agents. Phil Trans R Soc A 361:1089–1099

    PubMed  CAS  Google Scholar 

  • Maynard Smith J, Burian R, Kauffman S, Alberch P, Campbell J, Goodwin B, Lande R, Raup D, Wolpert L (1985) Developmental constraints and evolution: a perspective from the mountain lake conference on development and evolution. Q Rev Biol 60(3):265–286

    Google Scholar 

  • Orzack SH, Sober E (eds) (2001) Adaptationism and optimality. Cambridge University Press, Cambridge

    Google Scholar 

  • Pattee HH (1968) The physical basis of coding and reliability in biological evolution. In: Waddington CH (ed) Towards a theoretical biology, vol 1, Prolegomena. Edinburgh University Press, Edinburgh, pp 67–93

    Google Scholar 

  • Pattee HH (1972) Laws and constraints, symbols and languages. In: Waddington CH (ed) Towards a theoretical biology, vol 4, Essays. Edinburgh University Press, Edinburgh, pp 248–258

    Google Scholar 

  • Polanyi M (1968) Life’s irreducible structure. Science 160:1308–1312

    PubMed  CAS  Google Scholar 

  • Salthe SN (1985) Evolving hierarchical systems. Their structure and representation. Columbia University Press, New York

    Google Scholar 

  • Schwenk K, Wagner GP (2003) Constraint. In: Hall BK, Olson WM (eds) Keywords in evolutionary developmental biology. Harvard University Press, Cambridge, MA, pp 52–61

    Google Scholar 

  • Sommerfeld A (1952) Mechanics, 2nd edn. Academic, New York

    Google Scholar 

Download references

Acknowledgments

Funding for this work was provided by grants GV/EJ IT505-10 from the Government of the Basque Country, and FFI2011-25665 from the Ministerio de Economía y Competitivad (MEC) and FEDER funds from the E.C.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jon Umerez .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media, LLC

About this entry

Cite this entry

Umerez, J., Mossio, M. (2013). Constraint. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_56

Download citation

Publish with us

Policies and ethics