Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Edge Ontology

  • Jiguang WangEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_493



Inspired by  gene ontology, edge ontology provides a hierarchical vocabulary of terms for describing interactions between biological molecules. Different types of relationships between pathway components can be represented by edge ontology. Lu et al. (2007) provide a prototype of an edge ontology that divides edge into four levels: direction, type, subtype, and specification. Edge ontology is quite a novel concept still far from being completed.


  1. Lu LJ, Sboner A, Huang YJ, Lu HX, Gianoulis TA, Yip KY, Kim PM, Montelione GT, Gerstein MB. Comparing classical pathways and modern networks: towards the development of an edge ontology. Trends Biochem Sci. 2007;32(7):320–331.PubMedCrossRefGoogle Scholar

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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Beijing Institute of GenomicsChinese Academy of SciencesBeijingChina