Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Dense Overlapping Regulons

  • Guangxu JinEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_465



Dense overlapping regulons (DORs) were found in the Escherichia coli transcriptional regulation network. A set of operons, Z1, …, Zm, are each regulated by a combination of a set of input transcription factors, X1, …, Xm.


  1. Shen-Orr SS, Milo R, Mangan S, Alon U. Network motifs in the transcriptional regulation network of Escherichia coli. Nat Genet. 2002;31:64–8PubMedCrossRefGoogle Scholar

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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Systems Medicine and Bioengineering, Bioengineering and Bioinformatics Program, The Methodist Hospital Research InstituteWeill Medical College, Cornell UniversityHoustonUSA