Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Phylogenetic Footprinting

  • Jianhua Ruan
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_337

Definition

Phylogenetic footprinting is a technique used to identify transcription factor binding sites (TFBS) or other types of cis-regulatory elements by finding unusually well-conserved regions within a set of orthologous non-coding DNA sequences from multiple species.

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of Computer ScienceUniversity of Texas at San AntonioSan AntonioUSA