Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota


  • Jianhua Ruan
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_301


A segment of DNA usually occurring upstream from a gene and facilitating the transcription initiation of that gene. Promoters usually contain binding sites for RNA polymerase, general transcription factors, and specific transcription factors and other regulatory elements. In prokaryotes, the sequence of a promoter is recognized by the sigma (s) factor of the RNA polymerase. In eukaryotes, it is recognized by specific transcription factors.

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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of Computer ScienceUniversity of Texas at San AntonioSan AntonioUSA