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Personalized Medicine is the tailoring of medical treatment to individual characteristics. Individual characteristics may include: environmental factors (e.g., smoking), demographics (e.g., age, gender, ethnicity), patient history (e.g., previous medications, previous medical conditions), family history (e.g., disorders of direct relatives), and clinical profile (e.g., current weight, current medications, genetic profile). It is common for decisions made by clinical practitioners to be influenced by what they know about a patient, therefore, all medical practice is “personalized” to some extent. The Personalized Medicine concept is most commonly used in the context of genomic medicine (medical practice that incorporates knowledge of an individuals’ genetic profile and how certain profile characteristics give rise to certain phenotypes or physical conditions).
Predictive and Preventative Medicine
The two major components of Personalized...
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References
Hood L, Heath JR, Phelps ME, Lin B (2004) Systems biology and new technologies enable predictive and preventative medicine. Science 306(5696):640–643
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Personalized Medicine Coalition (2009) The case for personalized medicine. Personalized Medicine Coalition, Washington, DC. http://www.personalizedmedicinecoalition.org/about/about-personalized-medicine/the-case-for-personalized-medicine
President’s Council of Advisors on Science and Technology (2008) Priorities for personalized medicine: report of the President’s council of advisors on science and technology. President’s Council of Advisors on Science and Technology, Washington, DC
US National Cancer Institute, National Institutes of Health. Dictionary of cancer terms. www.cancer.gov/dictionary. Accessed 7 Sept 2010
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Overby, C.L. (2013). Personalized Medicine. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_237
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