Reference Work Entry

Encyclopedia of Systems Biology

pp 582-584

Disease Risk Assessment

  • Sanjeev KumarAffiliated withBioCOS Life Sciences Private Limited Email author 
  • , Shipra AgrawalAffiliated withBioCOS Life Sciences Pvt. Limited, Institute of Bioinformatics and Applied Biotechnology

Definition

Disease risk assessment could be defined as the systematic evaluation and identification of risk factors responsible for a disease, estimation of risk levels and finding possible ways to counter the onset and progression of a disease within the population. The following facts are very important and considered for disease risk assessment (Fig. 1):
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Disease Risk Assessment, Fig. 1

Factors involved in disease risk assessments: The information from evidence-based data (demographic, population-based data, and family history) is processed to get the SNP markers. The SNP marker data is used to predict the disease risk. An integrated approach from proteomics and genomics provide clues to identify predictive biomarkers (expression), which also help in disease risk assessment

  • Estimation of risk factors involves the evaluation of variables and factors which can be indicative of the likelihood development of a particular disease. For example, the risk factors such as age, smoking, ...

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