Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Elasticity Coefficient

  • Emma SaavedraEmail author
  • Rafael Moreno-Sánchez
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_1358

Definition

It is a quantitative value of the ability of a pathway enzyme (or group of enzymes) to change its rate or activity when changes in its ligands (substrates, products, activators, inhibitors) are varied during the pathway function. It is written as εaiX where a is the rate or activity of a pathway enzyme i and X is any of its ligands. The elasticities are positive for ligands that increase the enzyme rate whereas they are negative for those that decrease it. The elasticity coefficients are intrinsic properties of the enzymes since they only depend on its particular kinetic capabilities.

Cross-References

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of BiochemistryNational Institute for Cardiology “Ignacio Chávez”Mexico CityMexico