Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota


  • Sandra Orchard
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_1352



PSICQUIC is a web service enabling simultaneous computational access to multiple molecular interaction data resources (Aranda et al. 2011). A PSICQUIC query can be a simple protein identifier, or a complex construct using the syntax defined by the Molecular Interaction Query Language (MIQL), formulating the query once it is sufficient to retrieve the relevant data from many interaction data sources. Independently published observations of an experimental system, curated by independent databases, are then integrated in response to the query. All participating services are listed in the PSICQUIC Registry. The PSICQUIC project site (http://psicquic.googlecode.com/) offers open-source client libraries and code examples, facilitating programmatic access to the PSICQUIC Registry and services.



  1. Aranda B, Blankenburg H, Kerrien S, Brinkman FS, Ceol A, Chautard E, Dana JM, De Las RJ, Dumousseau M, Galeota E, Gaulton A, Goll J, Hancock RE, Isserlin R, Jimenez RC, Kerssemakers J, Khadake J, Lynn DJ, Michaut M, O'Kelly G, Ono K, Orchard S, Prieto C, Razick S, Rigina O, Salwinski L, Simonovic M, Velankar S, Winter A, Wu G, Bader GD, Cesareni G, Donaldson IM, Eisenberg D, Kleywegt GJ, Overington J, Ricard-Blum S, Tyers M, Albrecht M, Hermjakob H (2011) PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods 8:528–529PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.EMBL Outstation, European Bioinformatics Institute, HinxtonCambridgeUK