Skip to main content

Permutation Test

  • Reference work entry
Encyclopedia of Systems Biology

Definition

In a randomization test, we compute the null distribution of the test statistic by enumerating all possible treatment assignments. The number of treatment assignments, however, increases fast with the sample size. Instead, we can approximate the null distribution by randomly permuting the treatment labels and repeating the simulations a large number of times. To evaluate the hypothesis of no treatment effect using the permutation test, one needs to carry out the following:

  1. 1.

    Compute a relevant test statistic for collected data. The statistic is chosen so that it could differentiate between the null and the alternative.

  2. 2.

    Given the randomization scheme and under null, for large S, randomly simulate S treatment assignments and compute the corresponding test statistics for each permutation.

  3. 3.

    Use the simulated S values to construct the distribution of the test statistic under the null and compute the p-value of the test statistic.

Cross-References

Randomization Test...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 899.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Larissa Stanberry .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media, LLC

About this entry

Cite this entry

Stanberry, L. (2013). Permutation Test. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_1186

Download citation

Publish with us

Policies and ethics