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Thiothixene

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Synonyms

cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide; Navane; Thiothixene hydrochloride; Thiothixene hydrochloride intensol

Definition

Thiothixene is a prescription drug in the group of thioxanthenes in the family of first-generation antipsychotics which has the chemical formula C23H29N3O2S2. This drug was initially FDA-approved for medical use in the year 1967. This drug is FDA-approved for the treatment of schizophrenia and can be used to treat borderline personality disorder and schizotypal personality disorder. Observed side effects include drowsiness/sedation, insomnia/agitation, Parkinsonism, akathisia, and weight gain.

See Also

Antipsychotics: Drugs

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References and Readings

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  • Wilkaitis, J., Mulvihill, T., & Nasrallah, H. A. (2006). Classic antipsychotic medications. In A. F. Schatzberg & C. B. Nemeroff (Eds.), Essentials of clinical psychopharmacology (2nd ed., pp. 211–228). Washington, DC: American Psychiatric Publishing.

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Correspondence to Maureen Early .

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© 2013 Springer Science+Business Media New York

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Early, M., Wink, L., Erickson, C., McDougle, C.J. (2013). Thiothixene. In: Volkmar, F.R. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1698-3_842

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