Definition
The brand name of haloperidol in the United States is Haldol. Canadian brand names include Alti-Haloperidol, Apo-Haloperidol, Novo-Peridol, Peridol, Pms-Haloperidol, and Ratio-Haloperidol. It comes in three forms: a pill, an intramuscular injection, and a longacting depot decanoate form and is manufactured by Ortho-McNeil-Janssen Pharmaceuticals, Inc.
Indications
The oral and immediate-release injection forms of haloperidol are FDA-approved for the treatment of schizophrenia as well as for tics and vocal utterances associated with Tourette’s disorder (Janssen, 2005). These forms are also used as second-line treatment to manage hyperactivity in the pediatric population as well as for severe behavior problems, particularly combativeness, explosiveness, and hyperexcitability (Stahl, 2009). The long-acting depot intramuscular decanoate form of haloperidol is approved...
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References and Readings
Anderson, L. T., Campbell, M., et al. (1984). Haloperidol in the treatment of infantile autism: Effects on learning and behavioral symptoms. The American Journal of Psychiatry, 141(10), 1195–1202.
Anderson, L. T., Campbell, M., et al. (1989). The effects of haloperidol on discrimination learning and behavioral symptoms in autistic children. Journal of Autism and Developmental Disorders, 19(2), 227–239.
Campbell, M., Anderson, L. T., et al. (1978). A comparison of haloperidol and behavior therapy and their interaction in autistic children. Journal of the American Academy of Child Psychiatry, 17(4), 640–655.
Cohen, I. L., Campbell, M., et al. (1980). Behavioral effects of haloperidol in young autistic children. An objective analysis using a within-subjects reversal design. Journal of the American Academy of Child Psychiatry, 19(4), 665–677.
Faretra, G., Dooher, L., et al. (1970). Comparison of haloperidol and fluphenazine in disturbed children. The American Journal of Psychiatry, 126(11), 1670–1673.
Janssen-Cilag Pty Limited. (2005). Haldol product information. Retrieved from http://www.janssen.com.au/files/Products/Haldol_PI.pdf
Malone, R. P., & Waheed, A. (2009). The role of antipsychotics in the management of behavioural symptoms in children and adolescents with autism. Drugs, 69(5), 535–548.
Miral, S., Gencer, O., et al. (2008). Risperidone versus haloperidol in children and adolescents with AD: A randomized, controlled, double-blind trial. European Child & Adolescent Psychiatry, 17(1), 1–8.
Naruse, H., Nagahata, M., et al. (1982). A multi-center double-blind trial of pimozide (Orap), haloperidol and placebo in children with behavioral disorders, using crossover design. Acta Paedopsychiatrica, 48(4), 173–184.
Perry, R., Campbell, M., et al. (1989). Long-term efficacy of haloperidol in autistic children: Continuous versus discontinuous drug administration. Journal of the American Academy of Child and Adolescent Psychiatry, 28(1), 87–92.
Remington, G., Sloman, L., et al. (2001). Clomipramine versus haloperidol in the treatment of autistic disorder: A double-blind, placebo-controlled, crossover study. Journal of Clinical Psychopharmacology, 21(4), 440–444.
Stahl, S. M. (2008). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (3rd ed., pp. 328–342). New York: Cambridge University Press.
Stahl, S. M. (2009). Stahl’s essential psychopharmacology: The prescriber’s guide (3rd ed., pp. 237–242). New Delhi, India: Cambridge University Press.
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Doyle, C.A., McDougle, C.J. (2013). Haloperidol. In: Volkmar, F.R. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1698-3_826
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DOI: https://doi.org/10.1007/978-1-4419-1698-3_826
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