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Cerebrospinal Fluid

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CSF; Spinal fluid


Cerebrospinal Fluid (CSF) is a clear, colorless liquid with the consistency of water that fills the ventricular system and subarachnoid spaces around the brain and spinal cord. It is produced primarily by the ependymal cells in the choroid plexus and is absorbed via vesicular transport in the arachnoid villi. The production and absorption of CSF are continuous processes that normally occur at equal rates. These processes lead to the complete replacement of the total volume of CSF approximately three times a day. The circulation of CSF is also continuous. The direction of flow is from the lateral ventricles through the cerebral aqueduct, out either the foramina of Luschka or the foramen of Magendie, and downward posterior to the spinal cord. It then flows upward, anterior to the spinal cord and over the cerebral cortex.

CSF Composition

The CSF is sampled via lumbar puncture and is assayed to provide information relevant to diagnosis,...

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  • DOI: 10.1007/978-1-4419-1698-3_665
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References and Readings

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Correspondence to Keith A. Coffman .

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Coffman, K.A., Asato, M. (2013). Cerebrospinal Fluid. In: Volkmar, F.R. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY.

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