Encyclopedia of Behavioral Medicine

2013 Edition
| Editors: Marc D. Gellman, J. Rick Turner

Impaired Glucose Tolerance

  • Barbara Mullan
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-1005-9_1143

Synonyms

Definition

The US National Diabetes Data group (1979) first introduced the term impaired glucose tolerance (IGT) to indicate a state of increased risk of progressing to diabetes. It was defined to reduce the stigma of being labeled with diabetes and was also noted that many individuals with IGT could revert back to normal.

According to the World Health Organization and the International Diabetes Foundation (World Health Organization, 2006), IGT is diagnosed if 2-h plasma glucose levels are between 7.8 and 11.1 mmol/l or 140 mg/dl and 200 mg/dl as measured by the oral glucose tolerance test, or if fasting glucose levels are less than 7.0 mmol/l. Two-hour plasma glucose is the level of glucose or the venous plasma glucose 2 h after ingestion of 75 g of oral glucose load. Blood glucose levels normally rise after eating a meal and then gradually fall as the meal is digested. However, in people with impaired glucose tolerance, these levels remain elevated.

In...

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References and Readings

  1. Dunstan, D., Zimmet, P., Welborn, T., de Courten, M., Cameron, A., Colagiuri, S., et al. (2002). The rising prevalence of diabetes and impaired glucose tolerance: The Australian diabetes, obesity and lifestyle study. American Diabetes Association, 25(5), 829–834.Google Scholar
  2. Fuller, J. H., Shipley, M. J., Rose, G., Jarrett, R. J., & Keen, H. (1980). Coronary-heart-disease risk and impaired glucose tolerance The Whitehall Study. The Lancet, 315(8183), 1373–1376.CrossRefGoogle Scholar
  3. Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., et al. (1998). Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults. The third national health and nutrition examination survey, 1988–1994. Diabetes Care, 21(4), 518.PubMedCrossRefGoogle Scholar
  4. King, H., & Rewers, M. (1993). Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults. WHO Ad Hoc Diabetes Reporting Group. Diabetes Care, 16(1), 157.PubMedCrossRefGoogle Scholar
  5. National Diabetes Data Group. (1979). Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes, 28, 1039–1057.Google Scholar
  6. Orchard, T. J., Temprosa, M., Goldberg, R., Haffner, S., Ratner, R., Marcovina, S., et al. (2005). The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: The diabetes prevention program randomized trial. Annals of Internal Medicine, 142(8), 611.PubMedGoogle Scholar
  7. World Health Organization. (2006). Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia. Report of a WHO/IDF consultation. Retrieved November 1, 2010, from http://www.who.int/diabetes/publications/en/

Copyright information

© Springer Science+Business Media, New York 2013

Authors and Affiliations

  1. 1.Centre for Medical Psychology & Evidence-based Decision-making, University of SydneySydneyAustralia