Percutaneous Image-Guided Treatment of Pediatric Malignancy

  • William E. ShielsII
  • Mark J. Hogan
Reference work entry


Interventional radiologists continue to expand the diagnostic and therapeutic options available for pediatric oncology patients. Percutaneous radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) are performed safely in children, providing new adjuncts in the armamentarium of therapies for childhood cancer. Percutaneous image-guided radiofrequency ablation (RFA) provides a viable and effective therapeutic option in the treatment of benign and malignant solid tumors in a variety of locations to include the skeleton, liver, spleen, kidney, adrenal gland, lung, and pancreas. Primary and metastatic malignancies as large as 8 cm in children are now effectively treated with RFA. The most common indications for RFA in children include hepatoblastoma, hepatocellular carcinoma (HCC), metastatic osteosarcoma, and Wilms tumor. TACE is an additional therapy, safely performed in children, providing effective therapy options for children with multifocal hepatoblastoma, paraganglioma, neuroblastoma, HCC, osteogenic sarcoma, and Wilms tumor. When TACE and surgery are combined, blood loss and operative time are reduced, while providing more efficacious therapy when combined to surgery alone. In conclusion, RFA and TACE provide children with safe and effective options for treatment of pediatric malignancy.


Osteogenic Sarcoma Systemic Chemotherapy Orthotopic Liver Transplantation Gelatin Sponge Limb Salvage Surgery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Radiology, School of MedicineThe University of Toledo Medical CenterColumbusUSA

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