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Tumor Ablation: An Evolving Technology

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Image-Guided Cancer Therapy

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Abstract

Image-guided tumor ablation is a minimally invasive strategy to treat focal tumors by inducing irreversible cellular injury through the application of thermal, and more recently, nonthermal energy or chemical injection. This approach has become a widely accepted technique and is incorporated into the treatment of a range of clinical circumstances, including in the treatment of focal tumors in the liver, lung, kidney, bone, and adrenal glands. Given the multiplicity of treatment types and potential complexity of paradigms in oncology, and the wider application of thermal ablation techniques, a thorough understanding of the basic principles and recent advances in thermal ablation is a necessary prerequisite for their effective clinical use. This chapter will review several of these key concepts related to tumor ablation, including those that relate to performing a clinical ablation, such as understanding the goals of therapy and mechanisms of tissue heating or tumor destruction, and understanding the proper role of tumor ablation and the strategies that are being pursued to improve overall ablation outcome.

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Authors and Affiliations

  1. Department of Radiology, WCC 308-B, Beth Israel Deaconess Medical Center, Section of Interventional Radiology, 1 Deaconess Road, 02215, Boston, MA, USA

    Muneeb Ahmed

  2. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School Section of Interventional Radiology, 330 Brookline Avenue, 02215, Boston, MA, USA

    Beenish Tasawwar

  3. Department of Radiology, Hebrew University-Hadassah Medical Center, Kiryat Hadassah, 91120, Jerusalem, Israel

    S. Nahum Goldberg

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  1. Muneeb Ahmed
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  2. Beenish Tasawwar
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  3. S. Nahum Goldberg
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Correspondence to Muneeb Ahmed .

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Editors and Affiliations

  1. The Warren Alpert Medical School of Brown University, Department of Diagnostic Imaging Rhode Island Hospital, Providence, Rhode Island, USA

    Damian E. Dupuy

  2. Department of Surgery and Radiology Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Yuman Fong

  3. McMullen Consulting, LLC, Surprise, Arizona, USA

    William N. McMullen

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Ahmed, M., Tasawwar, B., Goldberg, S.N. (2013). Tumor Ablation: An Evolving Technology. In: Dupuy, D., Fong, Y., McMullen, W. (eds) Image-Guided Cancer Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0751-6_3

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